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Filtered Search Results
Apexbio Technology LLC LRRK2-IN-1 1234480-84-2 10mg
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LRRK2-IN-1 (CAS 1234480-84-2) is a selective small-molecule inhibitor of leucine-rich repeat kinase 2 (LRRK2) a cytoplasmic kinase implicated in Parkinson s disease and Crohn s disease pathogenesis LRRK2-IN-1 competitively inhibits ATP binding to LRRK2 demonstrating an in vitro IC50 of 13 nM against wild-type LRRK2 and 6 nM against the G2019S mutant In HEK293 cells expressing GFP-tagged wild-type or G2019S LRRK2 it shows dose-dependent inhibition with IC50 values of 0 17 M and 0 04 M respectively The compound displays selectivity towards LRRK2 over other kinases and does not affect LRRK1 LRRK2-IN-1 is utilized to investigate LRRK2 signaling pathways phosphorylation events and disease-related mutations in neurodegeneration and inflammation research
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eMolecules AstaTech / 4-TERT-BUTOXYANILINE / 0.25g / 721956548 / AB10504 / 95.000 / 57120-36-2 / MFCD11196184 / 165.236 / C10H15NO
AstaTech / 4-TERT-BUTOXYANILINE / 0.25g / 721956548 / AB10504 / 95.000 / 57120-36-2 / MFCD11196184 / 165.236 / C10H15NO
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eMolecules Medchem Express / CeMMEC13 / 5mg / 446256421 / HY-101088 / / 1790895-25-8 / MFCD30742989 / 336.347 / C19H16N2O4
Medchem Express / CeMMEC13 / 5mg / 446256421 / HY-101088 / / 1790895-25-8 / MFCD30742989 / 336.347 / C19H16N2O4
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000383178 BAY-8400 50MG
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Medchemexpress LLC HY-N0690 10mg Medchemexpress, Schisandrin C CAS:61301-33-5 Purity:>98%
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Medchemexpress, HY-N0690 10mg Schisandrin C CAS:61301-33-5 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Dihydrodiol-ibrutinib | 1654820-87-7 | 99.9% | 474.51 g/mol | C25H26N6O4 | 5 MG
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Dihydrodiol-ibrutinib is a dihydrodiol active metabolite of ibrutinib that retains BTK inhibitory activity at a lower potency than the parent compound. Supplied as a white to off-white solid for laboratory research use, it is suitable for in vitro assays and formulation studies and can be prepared in common solvents for dosing formulations.
- Active metabolite with measurable BTK inhibition (~15x lower than parent)
- High reported purity, suitable for research applications
- White to off-white solid for convenient handling
- Soluble in DMSO and compatible with multiple in vivo formulation vehicles
- Stable under recommended cold storage conditions for extended periods
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eMolecules Trimetazidine dihydrochloride | 13171-25-0 | MFCD00243086 | 25g
Matrix Scientific | Trimetazidine dihydrochloride | 25g | 389717704 | 12231 | 95.000 | 13171-25-0 | MFCD00243086 | 339.260 | C14H24Cl2N2O3
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eMolecules ChemScene / 1-(2-(Cyclopropylmethoxy)-6-hydroxyphenyl)ethanone / 250mg / 721433049 / CS-M0069 / 0.000 / 405239-70-5 / MFCD11553137 / 206.241 / C12H14O3
ChemScene / 1-(2-(Cyclopropylmethoxy)-6-hydroxyphenyl)ethanone / 250mg / 721433049 / CS-M0069 / 0.000 / 405239-70-5 / MFCD11553137 / 206.241 / C12H14O3
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eMolecules Medchem Express / Agomelatine (hydrochloride) / 5mg / 446268188 / HY-17038A / / 1176316-99-6 / MFCD28168055 / 279.760 / C15H18ClNO2
Medchem Express / Agomelatine (hydrochloride) / 5mg / 446268188 / HY-17038A / / 1176316-99-6 / MFCD28168055 / 279.760 / C15H18ClNO2
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![eMolecules Medchem Express / Bragsin2 / 5mg / 482203952 / HY-111550 / / 342795-08-8 / [null] / 289.166 / C11H6F3NO5](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502445802.PNG-250.jpg)
eMolecules Medchem Express / Bragsin2 / 5mg / 482203952 / HY-111550 / / 342795-08-8 / [null] / 289.166 / C11H6F3NO5
Medchem Express / Bragsin2 / 5mg / 482203952 / HY-111550 / / 342795-08-8 / [null] / 289.166 / C11H6F3NO5
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![eMolecules Medchem Express / Mertansine / 2mg / 446270342 / HY-19792 / / 139504-50-0 / [null] / 738.290 / C35H48ClN3O10S](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502445526.PNG-250.jpg)
eMolecules Medchem Express / Mertansine / 2mg / 446270342 / HY-19792 / / 139504-50-0 / [null] / 738.290 / C35H48ClN3O10S
Medchem Express / Mertansine / 2mg / 446270342 / HY-19792 / / 139504-50-0 / [null] / 738.290 / C35H48ClN3O10S
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Selleck Chemical LLC FPH2
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FPH2 (BRD-9424) is a small molecule which promotes differentiation of iPS-derived hepatocytes
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![eMolecules Medchem Express / Roflumilast N-oxide / 5mg / 446255847 / HY-100639 / / 292135-78-5 / [null] / 419.210 / C17H14Cl2F2N2O4](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502448912.PNG-250.jpg)
eMolecules Medchem Express / Roflumilast N-oxide / 5mg / 446255847 / HY-100639 / / 292135-78-5 / [null] / 419.210 / C17H14Cl2F2N2O4
Medchem Express / Roflumilast N-oxide / 5mg / 446255847 / HY-100639 / / 292135-78-5 / [null] / 419.210 / C17H14Cl2F2N2O4
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eMolecules Medchem Express / Tafluprost / 5mg / 446273054 / HY-B0600 / / 209860-87-7 / MFCD08062150 / 452.539 / C25H34F2O5
Medchem Express / Tafluprost / 5mg / 446273054 / HY-B0600 / / 209860-87-7 / MFCD08062150 / 452.539 / C25H34F2O5
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Enzo Life Sciences A-803467 (50mg). CAS: 944261-79-4
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A-803467 is a potent and selective inhibitor of the TTX-resistant voltage-gated sodium channel Nav1.8 which is preferentially expressed on sensory neurons. IC50 for human Nav1.8=8.0 nM (140 nM for rat). It attenuates neuropathic and inflammatory pain in various animal models. Purity: ≥98% (TLC). Solubility: Soluble in DMSO (15mg/ml) or 100% ethanol (2mg/ml). Long Term Storage: Ambient.
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